In vitro studies of multiwalled carbon nanotube/ultrahigh molecular weight polyethylene nanocomposites with osteoblast-like MG63 cells

In vitro studies of multiwalled carbon nanotube/ultrahigh molecular weight polyethylene nanocomposites with osteoblast-like MG63 cells.

Carbon nanotubes are highly versatile materials; new applications using them are continuously being developed. Special attention is being dedicated to the possible use of multiwalled carbon nanotubes in biomaterials contacting with bone. However, carbon nanotubes are also controversial in regards to effects exerted on living organisms. Carbon nanotubes can be used to improve the tribological pr...

Improved Wear Performance of Ultra High Molecular Weight Polyethylene Coated with Hydrogenated Diamond like Carbon

Internalized Gold Nanoparticles Do Not Affect the Osteogenesis and Apoptosis of MG63 Osteoblast-Like Cells: A Quantitative, In Vitro Study

The long-term toxicity effects of gold nanoparticles (GNPs) on the proliferation and differentiation of a progenitor cell line, MG63 osteoblast-like cells, was investigated. These cells were treated for 20 hours with two media that contained 10 nm GNPs at concentrations of 1 ppm and 10 ppm. The mitosis of the GNP-treated MG63 was observed after at least 21 hours using dark-field and fluorescenc...

Expression and localization of TASK-1, -2 and -3 channels in MG63 human osteoblast-like cells

It is well known that a number of ion channels are involved in the proliferation, migration and invasion of tumor cells. TASK channels, an acid-sensitive subgroup of the two-pore-domain K(+) channel (K2P) family, are expressed in numerous types of tissue and exhibit various physiological functions depending on the cell type. In the present study, we employed RT-PCR and western blot analysis to ...

Synthesis and characterization of multiwalled carbon nanotube reinforced ultra high molecular weight polyethylene composite by electrostatic spraying technique

In the present work, multiwalled carbon nanotube (MWNT) reinforced UHMWPE composite films were prepared by electrostatic spraying followed by consolidation. X-ray diffraction and differential scanning calorimetry studies showed a decrease in the crystallinity of UHMWPE due to the nature of the fabrication process as well as addition of MWNT. Tensile test showed an 82% increase in the Young’s mo...